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Crovalimab adjunct treatment for prevention of vaso-occlusive episodes in sickle cell disease
ISRCTN14514128Phase 2Completed
- Sponsor
- Roche
- Start
- Dec 2021
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
01
Overview
Phase 2, randomised, double-blind trial in sickle cell disease (SCD) comparing Crovalimab + standard therapy with Placebo + standard therapy (2 arms). Primary endpoint: Annualized rate of medical facility vaso-occlusive episodes. Started Dec 2021; status: completed.
02
Drugs
crovalimab
03
Conditions
sickle cell disease (SCD)
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