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CVD-Cog trial of isosorbide mononitrate and cilostazol after cortical or large subcortical stroke/TIA with cerebral small vessel disease

ISRCTN14632228Phase 2Recruiting

Sponsor
University of Nottingham
Start
Dec 2025
Modality
Small Molecules
01

Overview

Phase 2, randomised, open-label trial of isosorbide mononitrate and cilostazol in Cerebral Small Vessel Disease (CSVD), ischemic stroke and transient ischaemic attack (TIA) (5 arms), sponsored by University of Nottingham. Primary endpoint: Feasibility. Started Dec 2025; status: recruiting.

02

Drugs

isosorbide mononitratecilostazol
03

Conditions

Cerebral Small Vessel Disease (CSVD)ischemic stroketransient ischaemic attack (TIA)

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