Trial intelligence / Profile preview

OCTAVE-DUO COVID-19 revaccination trial in immunocompromised adults

ISRCTN15354495Phase 3Completed

Sponsor
University of Birmingham
Start
Jul 2021
Modality
Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Recombinant Proteins and Enzymes
01

Overview

Phase 3, randomised, open-label trial of tozinameran, elasomeran and NVX-CoV2373 in coronavirus disease 2019 (COVID-19) (5 arms), sponsored by University of Birmingham. Primary endpoints: Change in anti-spike SARS-CoV-2 antibody response at day 21 after re-boost and Change in SARS-CoV-2-specific T-cell response at day 21 after re-boost. Started Jul 2021; status: completed.

02

Drugs

tozinameranelasomeranNVX-CoV2373
03

Conditions

coronavirus disease 2019 (COVID-19)

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