Trial intelligence / Profile preview

Disulfiram plus zinc versus metronidazole for Entamoeba histolytica diarrhea

ISRCTN15356736Phase 2Recruiting

Sponsor
University of Florida
Start
Aug 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of disulfiram, zinc gluconate and metronidazole in amebiasis (3 arms), sponsored by University of Florida. Primary endpoints: Primary safety endpoint and Primary efficacy endpoint. Started Aug 2026; status: recruiting.

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Drugs

disulfiramzinc gluconatemetronidazole
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Conditions

amebiasis

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