Trial intelligence / Profile preview

AMETHYST trial of mifepristone added to methotrexate for tubal ectopic pregnancy

ISRCTN15446999Phase 3Recruiting

Sponsor
University of Aberdeen
Start
Apr 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial of mifepristone and methotrexate in Ectopic pregnancy (EP), sponsored by University of Aberdeen. Primary endpoint: Rate of surgery to treat tubal ectopic pregnancy. Started Apr 2026; status: recruiting.

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Drugs

mifepristonemethotrexate
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Conditions

Ectopic pregnancy (EP)

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