Trial intelligence / Profile preview

Three versus six cycles of platinum-based chemotherapy before maintenance avelumab in advanced bladder cancer

ISRCTN15750433Phase 2Active, not recruiting

Sponsor
Queen Mary University of London
Start
Dec 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
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Overview

Phase 2, randomised, open-label trial of avelumab, gemcitabine, cisplatin and carboplatin in transitional cell carcinoma (TCC) and bladder cancer (2 arms), sponsored by Queen Mary University of London. Primary endpoint: Quality of life. Started Dec 2021; status: active, not recruiting.

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Drugs

avelumabgemcitabinecisplatincarboplatin
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Conditions

transitional cell carcinoma (TCC)bladder cancer

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