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KJ-103 phase I/IIa trial in TROP2-positive advanced solid cancers

ISRCTN15819396Phase 2Recruiting

Sponsor
Cancer Research UK
Start
Jun 2026
Modality
Therapeutic Enzymes → Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 2, randomised, open-label trial of KJ-103 in Nonhematologic neoplasms, head and neck squamous cell carcinoma (HNSCC), transitional cell carcinoma (TCC) and 2 more (5 arms), sponsored by Cancer Research UK. Primary endpoints: Dose for expansion, Dose-limiting toxicities in Module A and 3 more. Started Jun 2026; status: recruiting.

02

Drugs

KJ-103
03

Conditions

Nonhematologic neoplasmshead and neck squamous cell carcinoma (HNSCC)transitional cell carcinoma (TCC)breast cancernon-small cell lung cancer (NSCLC)

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