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L-NAC for reversal of opioid-induced respiratory depression
ISRCTN16683564Phase 4Completed
- Sponsor
- Leiden University Medical Center
- Start
- Jun 2023
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
- Countries
- 1
01
Overview
Phase 4, randomised, double-blind trial of acetylcysteine and fentanyl in opioid-induced respiratory depression (OIRD) (2 arms), sponsored by Leiden University Medical Center. Primary endpoint: Minute ventilation. Started Jun 2023; status: completed.
02
Drugs
acetylcysteinefentanyl
03
Conditions
opioid-induced respiratory depression (OIRD)
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