Trial intelligence / Profile preview

Rituximab for nephrotic glomerulonephritis

ISRCTN16948923Phase 3Completed

Sponsor
Cambridge University Hospitals NHS Foundation Trust
Start
Jul 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 3, randomised, double-blind trial in nephrosis and focal segmental glomerulosclerosis (FSGS) comparing Rituximab + prednisolone with Placebo + prednisolone (2 arms). Primary endpoint: Time from partial or complete remission to relapse of nephrotic syndrome. Started Jul 2019; status: completed.

02

Drugs

rituximab
03

Conditions

nephrosisfocal segmental glomerulosclerosis (FSGS)

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