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High-dose antibiotics plus methenamine hippurate versus standard care for chronic urinary tract infection

ISRCTN17592593Phase 2Recruiting

Sponsor
University College London Comprehensive Clinical Trials Unit
Start
Feb 2026
Modality
Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial of cefalexin, nitrofurantoin, trimethoprim, methenamine hippurate and amoxicillin in urinary tract infection (UTI) (2 arms), sponsored by University College London Comprehensive Clinical Trials Unit. Started Feb 2026; status: recruiting.

02

Drugs

cefalexinnitrofurantointrimethoprimmethenamine hippurateamoxicillin
03

Conditions

urinary tract infection (UTI)

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