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MARCH trial of mucoactives for airway clearance in mechanically ventilated acute respiratory failure

ISRCTN17683568Phase 3Completed

Sponsor
Belfast Health and Social Care Trust
Start
Feb 2022
Modality
Small Molecules
01

Overview

Phase 3, randomised, open-label trial of carbocisteine and hypertonic saline in acute respiratory decompensation (4 arms), sponsored by Belfast Health and Social Care Trust. Primary endpoint: Duration of mechanical ventilation. Started Feb 2022; status: completed.

02

Drugs

carbocisteinehypertonic saline
03

Conditions

acute respiratory decompensation

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