Trial intelligence / Profile preview

PRIME-RT trial in locally advanced rectal cancer

ISRCTN18138369Phase 2Completed

Sponsor
NHS Greater Glasgow and Clyde
Start
Jan 2021
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial of durvalumab, oxaliplatin, fluorouracil, folinic acid and capecitabine in rectal adenocarcinoma (4 arms), sponsored by NHS Greater Glasgow and Clyde. Primary endpoint: Complete response rate at 6 months. Started Jan 2021; status: completed.

02

Drugs

durvalumaboxaliplatinfluorouracilfolinic acidcapecitabine
03

Conditions

rectal adenocarcinoma

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