Trial intelligence / Profile preview

DNA HIV-C prime and NYVAC HIV-C boost schedule comparison

ISRCTN20946776Phase 2Completed

Sponsor
EuroVacc Foundation
Start
Jun 2007
Modality
Prophylactic Vaccines → Vaccines & Immunotherapeutics, DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Viral Vector Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
01

Overview

Phase 2, randomised, open-label trial of DNA HIV-C and NYVAC HIV-C in human immunodeficiency virus infection (HIV) (2 arms), sponsored by EuroVacc Foundation. Primary endpoints: CD8/CD4+ T-cell response by IFN-gamma ELISPOT at weeks 26 and 28, Grade 3 or above local adverse events and 3 more. Started Jun 2007; status: completed.

02

Drugs

DNA HIV-CNYVAC HIV-C
03

Conditions

human immunodeficiency virus infection (HIV)

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