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Non-surgical management trial for mandibular osteoradionecrosis
ISRCTN34217298Phase 2Active, not recruiting
- Sponsor
- University of Liverpool
- Start
- Apr 2023
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
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Overview
Phase 2, randomised, open-label trial of pentoxifylline, tocopherol and clodronate in Mandibular osteoradionecrosis (ORN) (2 arms), sponsored by University of Liverpool. Primary endpoint: Time to healing. Started Apr 2023; status: active, not recruiting.
02
Drugs
pentoxifyllinetocopherolclodronate
03
Conditions
Mandibular osteoradionecrosis (ORN)
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