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Feasibility randomized trial of CTD versus stem cell transplantation or Mel-Dex in systemic AL amyloidosis

ISRCTN34235460Phase 3Completed

Sponsor
University College London
Start
Jan 2007
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
01

Overview

Phase 3, randomised, open-label trial of cyclophosphamide, thalidomide, dexamethasone and melphalan in light-chain amyloidosis (4 arms), sponsored by University College London. Primary endpoints: Clonal response, Toxicity and safety and 1 more. Started Jan 2007; status: completed.

02

Drugs

cyclophosphamidethalidomidedexamethasonemelphalan
03

Conditions

light-chain amyloidosis

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