Trial intelligence / Profile preview

Olaparib in relapsed/refractory CLL, mantle cell lymphoma, and T-PLL

ISRCTN34386131Phase 2Completed

Sponsor
University of Birmingham
Start
Mar 2010
Modality
Small Molecules
01

Overview

Phase 2, open-label trial of olaparib in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma (MCL) and T-cell prolymphocytic leukemia (T-PLL) (3 arms), sponsored by University of Birmingham. Primary endpoint: Clinical response rate at 16 weeks in ATM-deficient relapsed/refractory CLL. Started Mar 2010; status: completed.

02

Drugs

olaparib
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)mantle cell lymphoma (MCL)T-cell prolymphocytic leukemia (T-PLL)

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