Trial intelligence / Profile preview

National Lung Matrix Trial in non-small cell lung cancer

ISRCTN38344105Phase 2Completed

Sponsor
University of Birmingham
Start
Mar 2015
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 2, open-label trial of fexagratinib, vistusertib, palbociclib, crizotinib, selumetinib and 6 more in non-small cell lung cancer (NSCLC) (10 arms), sponsored by University of Birmingham. Primary endpoints: Objective response, Durable clinical benefit and 1 more. Started Mar 2015; status: completed.

02

Drugs

fexagratinibvistusertibpalbociclibcrizotinibselumetinib
03

Conditions

non-small cell lung cancer (NSCLC)

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