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MiST phase II stratified therapy trial in relapsed malignant mesothelioma

ISRCTN39816629Phase 2Completed

Sponsor
University of Leicester
Start
Jan 2019
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

Phase 2, open-label trial of rucaparib, abemaciclib, pembrolizumab, bemcentinib, atezolizumab and 3 more in mesothelioma (5 arms), sponsored by University of Leicester. Primary endpoint: Disease control rate at 12 weeks. Started Jan 2019; status: completed.

02

Drugs

rucaparibabemaciclibpembrolizumabbemcentinibatezolizumab
03

Conditions

mesothelioma

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