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Alemtuzumab, dexamethasone, and lenalidomide induction with randomised lenalidomide maintenance in high-risk CLL

ISRCTN40303610Phase 2Completed

Sponsor
University of Liverpool
Start
Sep 2011
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
01

Overview

Phase 2, randomised, open-label trial of alemtuzumab, dexamethasone and lenalidomide in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) (2 arms), sponsored by University of Liverpool. Primary endpoints: Complete response and Complete response with incomplete blood count recovery. Started Sep 2011; status: completed.

02

Drugs

alemtuzumabdexamethasonelenalidomide
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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