Trial intelligence / Profile preview

Phase III revumenib plus intensive chemotherapy in newly diagnosed NPM1-mutated AML

ISRCTN42617850Phase 3Recruiting

Sponsor
Syndax Pharmaceuticals
Start
Mar 2026
Modality
Small Molecules
01

Overview

Phase 3, randomised trial in acute myeloid leukemia (AML) comparing Experimental Arm: Revumenib + Intensive Chemotherapy with Placebo + Intensive Chemotherapy (2 arms). Primary endpoints: Event-Free Survival and Minimal Residual Disease in Bone Marrow Negative Complete Response Rate. Started Mar 2026; status: recruiting.

02

Drugs

revumenib
03

Conditions

acute myeloid leukemia (AML)

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