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REALITY trial to reduce early mortality after ART initiation in advanced HIV

ISRCTN43622374Phase 3Completed

Sponsor
Medical Research Council
Start
Jun 2013
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
01

Overview

Phase 3, randomised, open-label trial of trimethoprim + sulfamethoxazole, isoniazid, fluconazole, albendazole and azithromycin in human immunodeficiency virus infection (HIV) (6 arms), sponsored by Medical Research Council. Primary endpoint: Mortality through 24 weeks after ART initiation. Started Jun 2013; status: completed.

02

Drugs

trimethoprim + sulfamethoxazoleisoniazidfluconazolealbendazoleazithromycin
03

Conditions

human immunodeficiency virus infection (HIV)

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