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Fulvestrant with or without anastrozole versus exemestane in ER-positive advanced or metastatic breast cancer after non-steroidal aromatase inhibitor progression

ISRCTN44195747Phase 3Completed

Sponsor
Royal Marsden NHS Foundation Trust
Start
Mar 2004
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in breast cancer comparing Fulvestrant plus placebo, Fulvestrant plus anastrozole and Exemestane (3 arms). Primary endpoint: Progression-free survival. Started Mar 2004; status: completed.

02

Drugs

fulvestrantanastrozoleexemestane
03

Conditions

breast cancer

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