Trial intelligence / Profile preview

Rituximab-iCHOP versus rituximab high-dose sequential therapy with autologous stem cell transplantation for high-risk DLBCL

ISRCTN46136861Phase 3Completed

Sponsor
HOVON
Start
Oct 2005
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone and 6 more in diffuse large B-cell lymphoma (DLBCL) and non-Hodgkin lymphoma (NHL) (2 arms), sponsored by HOVON. Primary endpoint: Event-free survival. Started Oct 2005; status: completed.

02

Drugs

rituximabcyclophosphamidedoxorubicinvincristineprednisone
03

Conditions

diffuse large B-cell lymphoma (DLBCL)non-Hodgkin lymphoma (NHL)

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