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Low-dose colchicine in high-risk coronary artery disease with residual inflammation

ISRCTN46375134Phase 4Completed

Sponsor
King's College Hospital
Start
Jun 2024
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
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Overview

Phase 4, randomised, open-label trial of colchicine in coronary arteriosclerosis, atherosclerosis, Chronic Coronary Syndrome (CCS) and 1 more (2 arms), sponsored by King's College Hospital. Primary endpoint: Minimal fibrous cap thickness. Started Jun 2024; status: completed.

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Drugs

colchicine
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Conditions

coronary arteriosclerosisatherosclerosisChronic Coronary Syndrome (CCS)chronic inflammation

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