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POLB 001 with teclistamab to prevent severe immune reactions in relapsed or refractory multiple myeloma

ISRCTN50499387Phase 2Recruiting

Sponsor
DIDACT Foundation
Start
Mar 2026
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Small Molecules
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Overview

Phase 2, open-label trial of POLB 001 and teclistamab in multiple myeloma (MM) (2 arms), sponsored by DIDACT Foundation. Primary endpoints: Incidence of adverse events, Severity of adverse events and 2 more. Started Mar 2026; status: recruiting.

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Drugs

POLB 001teclistamab
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Conditions

multiple myeloma (MM)

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