Trial intelligence / Profile preview

FLAMSA-BU versus standard reduced-intensity conditioning before allogeneic stem cell transplantation in AML and MDS

ISRCTN50855000Phase 2Completed

Sponsor
University of Birmingham
Start
Oct 2013
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial of fludarabine, cytarabine, amsacrine, busulfan, melphalan and 2 more in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) (2 arms), sponsored by University of Birmingham. Primary endpoint: Overall survival. Started Oct 2013; status: completed.

02

Drugs

fludarabinecytarabineamsacrinebusulfanmelphalan
03

Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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