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TACTIC-R platform trial for candidate COVID-19 treatments in hospitalized adults

ISRCTN57085639Phase 2Completed

Sponsor
University Hospital Southampton NHS Foundation Trust
Start
May 2020
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Cyclic Peptides → Modified Peptides → Peptides
01

Overview

Phase 2, randomised, open-label trial of bemcentinib, tozorakimab, acalabrutinib and zilucoplan in coronavirus disease 2019 (COVID-19) (5 arms), sponsored by University Hospital Southampton NHS Foundation Trust. Primary endpoint: Time to clinical improvement. Started May 2020; status: completed.

02

Drugs

bemcentinibtozorakimabacalabrutinibzilucoplan
03

Conditions

coronavirus disease 2019 (COVID-19)

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