Trial intelligence / Profile preview

R21/Matrix-M malaria vaccine safety and immunogenicity study in Thai adults

ISRCTN57717892Phase 2Completed

Sponsor
University of Oxford
Start
Jan 2023
Modality
Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in malaria comparing R21/Matrix-M + dihydroartemisinin + piperaquine + primaquine, R21/Matrix-M only and dihydroartemisinin + piperaquine + primaquine only (3 arms). Primary endpoints: Solicited adverse events, Unsolicited adverse events and 1 more. Started Jan 2023; status: completed.

02

Drugs

R21/Matrix-Mdihydroartemisininpiperaquineprimaquine
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Conditions

malaria

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