Trial intelligence / Profile preview

Methotrexate added to standard immunosuppression for prevention of liver allograft rejection

ISRCTN58758525Phase 2Completed

Sponsor
United States Department of Health and Human Services
Start
Jan 2004
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01

Overview

Phase 2, randomised trial of methotrexate in Hepatic transplant rejection (LTR) (2 arms), sponsored by United States Department of Health and Human Services. Primary endpoints: Adverse effects attributable to immunosuppressant therapy and Incidence and severity of early graft rejection episodes. Started Jan 2004; status: completed.

02

Drugs

methotrexate
03

Conditions

Hepatic transplant rejection (LTR)

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