Trial intelligence / Profile preview

Neoadjuvant and adjuvant chemotherapy versus neoadjuvant chemoradiation for oesophageal and oesophago-gastric junction adenocarcinoma

ISRCTN60280514Phase 3Completed

Sponsor
Cancer Trials Ireland
Start
Mar 2015
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
01

Overview

Phase 3, randomised, open-label trial of epirubicin, cisplatin, capecitabine, fluorouracil, oxaliplatin and 2 more in adenocarcinoma of the lower esophagus and gastroesophageal adenocarcinoma (2 arms), sponsored by Cancer Trials Ireland. Primary endpoint: Overall survival at 1, 2, and 3 years. Started Mar 2015; status: completed.

02

Drugs

epirubicincisplatincapecitabinefluorouraciloxaliplatin
03

Conditions

adenocarcinoma of the lower esophagusgastroesophageal adenocarcinoma

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