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Fluid expansion in severe malnutrition
ISRCTN61146418Phase 2Completed
- Sponsor
- University of Oxford
- Start
- Jan 2007
- Modality
- Small Molecules, Recombinant Proteins and Enzymes, Cell Therapies
- Countries
- 1
01
Overview
Phase 2, randomised, open-label trial of lactated ringer's solution, albumin (human), half-strength Darrow's solution in 5% dextrose and low-titer group O whole blood in severe acute malnutrition (SAM), hypovolemia and Shock (5 arms), sponsored by University of Oxford. Primary endpoint: Resolution of features of shock at 4 hours. Started Jan 2007; status: completed.
02
Drugs
lactated ringer's solutionalbumin (human)half-strength Darrow's solution in 5% dextroselow-titer group O whole blood
03
Conditions
severe acute malnutrition (SAM)hypovolemiaShock
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