Trial intelligence / Profile preview

TASTER trial in TKI-resistant chronic myeloid leukaemia

ISRCTN68270067Phase 2Terminated

Sponsor
NHS Greater Glasgow and Clyde
Start
Aug 2019
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
01

Overview

Phase 2, randomised, open-label trial of tazemetostat, idasanutlin, imatinib, nilotinib, dasatinib and 2 more in chronic myelogenous leukemia (CML) (3 arms), sponsored by NHS Greater Glasgow and Clyde. Primary endpoint: Treatment responder rate. Started Aug 2019; status: terminated.

02

Drugs

tazemetostatidasanutlinimatinibnilotinibdasatinib
03

Conditions

chronic myelogenous leukemia (CML)

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