Trial intelligence / Profile preview

Teclistamab or talquetamab combinations versus DRd in newly diagnosed multiple myeloma

ISRCTN72661732Phase 3Recruiting

Sponsor
Janssen Pharmaceutical
Start
Oct 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
01

Overview

Phase 3, randomised, open-label trial of teclistamab, talquetamab, daratumumab, lenalidomide and dexamethasone in multiple myeloma (MM) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Progression-free survival and 12-month MRD-negative complete response. Started Oct 2022; status: recruiting.

02

Drugs

teclistamabtalquetamabdaratumumablenalidomidedexamethasone
03

Conditions

multiple myeloma (MM)

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