Trial intelligence / Profile preview

Phase 3 study of talquetamab-based regimens versus EPd or PVd in relapsed or refractory multiple myeloma

ISRCTN74178658Phase 3Active, not recruiting

Sponsor
Janssen Pharmaceutical
Start
Jan 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
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Overview

Phase 3, randomised, open-label trial of talquetamab, teclistamab, elotuzumab, pomalidomide, bortezomib and 1 more in multiple myeloma (MM) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Progression-free survival. Started Jan 2024; status: active, not recruiting.

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Drugs

talquetamabteclistamabelotuzumabpomalidomidebortezomib
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Conditions

multiple myeloma (MM)

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