Trial intelligence / Profile preview

BEACH 301 phase II study of TYRA-300 in children with achondroplasia

ISRCTN77260709Phase 2Recruiting

Sponsor
Tyra Biosciences
Start
Aug 2025
Modality
Small Molecules
01

Overview

Phase 2, open-label trial of dabogratinib in achondroplasia (ACH) (3 cohorts), sponsored by Tyra Biosciences. Primary endpoints: Incidence of treatment-related adverse events and Change from baseline in annualized growth velocity. Started Aug 2025; status: recruiting.

02

Drugs

dabogratinib
03

Conditions

achondroplasia (ACH)

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