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Methotrexate for pain reduction in knee osteoarthritis
ISRCTN77854383Phase 3Completed
- Sponsor
- University of Leeds
- Start
- May 2014
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
01
Overview
Phase 3, randomised, double-blind trial in knee osteoarthritis (OA) comparing Methotrexate plus usual pain management with Placebo plus usual pain management (2 arms). Primary endpoint: Average overall knee pain severity. Started May 2014; status: completed.
02
Drugs
methotrexate
03
Conditions
knee osteoarthritis (OA)
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