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REFINE reduced-intensity immunotherapy trial across renal cancer and melanoma

ISRCTN79455488Phase 2Completed

Sponsor
University College London
Start
May 2022
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
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Overview

Phase 2, randomised, open-label trial of nivolumab, ipilimumab and pembrolizumab in renal cell carcinoma (RCC) and melanoma (2 arms), sponsored by University College London. Primary endpoint: Progression-free survival. Started May 2022; status: completed.

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Drugs

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Conditions

renal cell carcinoma (RCC)melanoma

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