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COBALT trial of memantine added to cholinesterase inhibitor therapy in Lewy body dementia

ISRCTN79794378Phase 3Active, not recruiting

Sponsor
Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust
Start
Nov 2022
Modality
Small Molecules
01

Overview

Phase 3, randomised, double-blind trial in dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) comparing Memantine add-on with Placebo add-on (2 arms). Primary endpoint: Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change. Started Nov 2022; status: active, not recruiting.

02

Drugs

memantine
03

Conditions

dementia with Lewy bodies (DLB)Parkinson's disease dementia (PDD)

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