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PANTHER trial in hypoxaemic acute respiratory failure
ISRCTN81435672Phase 2Recruiting
- Sponsor
- Imperial College London
- Start
- Nov 2025
- Modality
- Small Molecules, Recombinant Proteins and Enzymes, Antibody-Based Therapeutics
01
Overview
Phase 2, randomised, open-label trial of simvastatin and baricitinib in acute respiratory distress syndrome (ARDS) and Acute hypoxaemic respiratory failure (AHRF) (3 arms), sponsored by Imperial College London. Primary endpoint: 28-day organ support-free days. Started Nov 2025; status: recruiting.
02
Drugs
simvastatinbaricitinib
03
Conditions
acute respiratory distress syndrome (ARDS)Acute hypoxaemic respiratory failure (AHRF)
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