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Aspirin esomeprazole chemoprevention trial in Barrett's oesophagus

ISRCTN85156844Phase 3Completed

Sponsor
University of Oxford
Start
Mar 2005
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
01

Overview

Phase 3, randomised trial of esomeprazole and aspirin in Barrett's esophagus (4 arms), sponsored by University of Oxford. Primary endpoints: Composite of all-cause mortality, oesophageal adenocarcinoma, and high-grade dysplasia, Conversion to oesophageal adenocarcinoma and 2 more. Started Mar 2005; status: completed.

02

Drugs

esomeprazoleaspirin
03

Conditions

Barrett's esophagus

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