Trial intelligence / Profile preview

EXCITE for locally advanced rectal cancer

ISRCTN86285819Phase 2Completed

Sponsor
University College London
Start
Mar 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
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Overview

Phase 2, open-label, single-arm trial of cetuximab, capecitabine and irinotecan in rectal cancer and rectal adenocarcinoma, sponsored by University College London. Primary endpoint: Histologically confirmed R0 resection rate. Started Mar 2009; status: completed.

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Drugs

cetuximabcapecitabineirinotecan
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Conditions

rectal cancerrectal adenocarcinoma

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