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Inhaled fluticasone as emergency rescue treatment in adults with adrenal insufficiency
ISRCTN88499808Phase 2Recruiting
- Sponsor
- Newcastle Hospitals NHS Foundation Trust
- Start
- Jun 2025
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
01
Overview
Phase 2, randomised, open-label trial of Flixocort, hydrocortisone, apomorphine and naloxone in hypoadrenocorticism, Addison's disease and Adrenocorticotropic hormone (4 arms), sponsored by Newcastle Hospitals NHS Foundation Trust. Primary endpoints: Plasma ACTH response, Serum fluticasone levels during nausea/vomiting and 1 more. Started Jun 2025; status: recruiting.
02
Drugs
Flixocorthydrocortisoneapomorphinenaloxone
03
Conditions
hypoadrenocorticismAddison's diseaseAdrenocorticotropic hormone
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