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GOTHAM trial of gemtuzumab ozogamicin for relapsed/refractory HLH, MAS, or solid tumors

ISRCTN89158144Phase 2Completed

Sponsor
University of Birmingham
Start
Jun 2021
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
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Overview

Phase 2, open-label trial of gemtuzumab ozogamicin in haemophagocytic lymphohistiocytosis (HLH), macrophage activation syndrome (MAS) and Nonhematologic neoplasms (2 arms), sponsored by University of Birmingham. Started Jun 2021; status: completed.

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Drugs

gemtuzumab ozogamicin
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Conditions

haemophagocytic lymphohistiocytosis (HLH)macrophage activation syndrome (MAS)Nonhematologic neoplasms

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