Trial intelligence / Profile preview

Thiopurine continuation versus withdrawal during switch from intravenous to subcutaneous infliximab in inflammatory bowel disease

ISRCTN95420128Phase 4Completed

Sponsor
King's Health Partners
Start
Oct 2022
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, randomised, open-label trial of infliximab, azathioprine and mercaptopurine in Crohn's disease, autoimmune colitis and inflammatory bowel disease (IBD) (2 arms), sponsored by King's Health Partners. Primary endpoint: Free anti-drug antibody positivity at week 24. Started Oct 2022; status: completed.

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Drugs

infliximabazathioprinemercaptopurine
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Conditions

Crohn's diseaseautoimmune colitisinflammatory bowel disease (IBD)

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