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CHOICES trial of DIR/POS/NES in adults with cystic fibrosis without access to approved CFTR modulators

ISRCTN96750019Phase 2Completed

Sponsor
University Medical Center Utrecht
Start
May 2024
Modality
Small Molecules
01

Overview

Phase 2, randomised, double-blind trial of posaconazole and Nestorone Ring in cystic fibrosis (CF) (2 arms), sponsored by University Medical Center Utrecht. Primary endpoint: Mean percent predicted forced expiratory volume in 1 second. Started May 2024; status: completed.

02

Drugs

posaconazoleNestorone Ring
03

Conditions

cystic fibrosis (CF)

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