Trial intelligence / Profile preview

ADMIRAL study of multiple ascending doses of STK-001 in pediatric Dravet syndrome

ISRCTN99651026Phase 2Completed

Sponsor
Stoke Therapeutics
Start
Jul 2021
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

Phase 2, open-label trial of zorevunersen in Dravet syndrome (3 cohorts), sponsored by Stoke Therapeutics. Primary endpoints: Safety and tolerability, Plasma pharmacokinetics of STK-001 and 1 more. Started Jul 2021; status: completed.

02

Drugs

zorevunersen
03

Conditions

Dravet syndrome

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