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Phase II trial of oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab in high-risk rectal cancer

ISRCTN99828560Phase 2Completed

Sponsor
Royal Marsden NHS Foundation Trust
Start
Sep 2005
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
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Overview

Phase 2, randomised, open-label trial of cetuximab, oxaliplatin and capecitabine in rectal cancer (2 arms), sponsored by Royal Marsden NHS Foundation Trust. Primary endpoint: Pathological complete response at total mesorectal excision. Started Sep 2005; status: completed.

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Drugs

cetuximaboxaliplatincapecitabine
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Conditions

rectal cancer

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