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Effects of pharmacological treatments on hemodynamics, cardiovascular reserve, exercise tolerance, and prognosis in HFpEF

jRCT1031220336Recruiting

Start
Sep 2022
Modality
Small Molecules
Countries
1
01

Overview

Open-label, single-arm trial of empagliflozin, sacubitril + valsartan and spironolactone in heart failure with preserved ejection fraction (HFpEF). Primary endpoint: Change in estimated pulmonary artery systolic pressure during peak exercise. Started Sep 2022; status: recruiting.

02

Drugs

empagliflozinsacubitril + valsartanspironolactone
03

Conditions

heart failure with preserved ejection fraction (HFpEF)

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