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PRESERVE-HF trial (Empagliflozin in underweight HFpEF patients)

jRCT1031250547Recruiting

Sponsor
Grant-in-Aid for Scientific Research (KAKENHI), Gunma Foundation for Medical and Health science
Start
Dec 2025
Modality
Small Molecules
Countries
1
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Overview

Open-label, single-arm trial of empagliflozin in heart failure with preserved ejection fraction (HFpEF), sponsored by Grant-in-Aid for Scientific Research (KAKENHI), Gunma Foundation for Medical and Health science. Primary endpoint: Change in skeletal muscle mass index from baseline to 4 months. Started Dec 2025; status: recruiting.

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Drugs

empagliflozin
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Conditions

heart failure with preserved ejection fraction (HFpEF)

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