Trial intelligence / Profile preview

J-PROMISE: Prospective observational study of first-line nivolumab plus ipilimumab in unresectable hepatocellular carcinoma in Japan

jRCT1031250756Recruiting

Sponsor
Bristol Myers Squibb
Start
Mar 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Open-label, single-arm trial of nivolumab and ipilimumab in hepatocellular carcinoma (HCC), sponsored by Bristol Myers Squibb. Primary endpoints: Safety profile of grade 3 or higher immune-mediated liver injury, Effectiveness: objective response rate, best overall response, disease control rate and 1 more. Started Mar 2026; status: recruiting.

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Drugs

nivolumabipilimumab
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Conditions

hepatocellular carcinoma (HCC)

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